![]() ![]() In the present study, we employed DNA fiber analysis to investigate how pluripotent stem cells are reprogrammed into totipotent-like 2-cell-like cells (2CLCs). Totipotency emerges in early embryogenesis, but its molecular underpinnings remain poorly characterized. Nature Genetics volume 54, pages 318–327 ( 2022) Cite this article DNA replication fork speed underlies cell fate changes and promotes reprogramming
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